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We performed in silico prediction of mitochondrial targeting signals in the predicted Monocercomonoides sp. proteome and identified 107 candidate proteins (Figure 2A; Experimental Procedures; Table S6A). The presence of a predicted targeting signal by itself does not prove the targeting, as such amino acid sequences can also appear at random [27]. Functional annotation revealed that a majority of proteins recovered by this search fall into the Kyoto Encyclopedia of Genes and Genomes (KEGG) category “genetic information processing.” Given the absence of a mitochondrial genome, or organellar translation machinery, it is unlikely that these proteins function in an MRO.
Ученые нашли микробов, которые не должны существовать